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Brief facts about dmcm:
DMCM is a drug from the β-carboline family that induces anxiety and convulsions by acting as a negative allosteric modulator of GABAA receptors — functionally opposite to benzodiazepines and related drugs which are positive allosteric modulators — and is used in scientific research for these properties to test new anxiolytic and anticonvulsant medications, respectively. It has also been shown to produce analgesic effects in animals, which is thought to be the drug's induced panic reducing the perception of pain.
GABAA receptor negative allosteric modulator - A GABAA receptor negative allosteric modulator is a negative allosteric modulator, or inhibitor, of the GABAA receptor, a ligand-gated ion channel of the major inhibitory neurotransmitter γ-aminobutyric acid. They are closely related and similar to GABAA receptor antagonists.
GABAA receptor negative allosteric modulators
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